The Impact of the Human Microbiome on Mental Health: A Systemic Review

Abstract

Background: There is growing evidence to suggest that the human microbiome, the trillions of microorganisms that reside in and on our bodies, can impact mental health. However, the exact mechanisms underlying this relationship and the clinical implications of these findings are still being explored. Methods: In this systematic review, the author searched multiple databases for studies examining the relationship between the human microbiome and mental health. The studies included in the review spanned both animal and human research and included both observational and interventional studies. Results: The author found that there is evidence to suggest that changes in the gut microbiome can impact mood, behaviour and cognitive function. Specifically, alterations in the gut microbiome have been associated with anxiety, depression, and stress-related disorders. The author also found that certain probiotics and prebiotics, as well as faecal microbiota transplantation, may have potential as therapies for these conditions. Conclusion: The relationship between the human microbiome and mental health is a complex and rapidly evolving area of research. While the evidence to date suggests that the microbiome can play a role in mental health disorders, further research is needed to better understand the mechanisms underlying this relationship and to develop safe and effective microbiome-based therapies for these conditions.