Abstract

The aim of this study was to assess the impact of the nationwide total lockdown (LD) in France on weight loss and body composition modifications in subjects participating in a weight loss program and to evaluate the impact of remote consultations on participants’ adherence to the weight loss program. The CO-RNPC study was a prospective multicentre cohort study including participants undergoing a two to six months program. The rate of weight loss in kg/week was computed before (15 days), during (99 days) and after LD (15 days). In the 1550 completing participants, body weight decreased from 87.1 kg [IQR 77.0; 100.2] to 82.3 kg [72.1; 94.3] resulting in a difference of −4.79 kg [−4.48; −5.10] (p < 0.01), with a corresponding reduction in waist circumference by 4 cm ([0; 9], p < 0.01). The median weight loss was 4.4 kg [0.5; 9.4] in those who used remote consultations, and 1.4 kg [0.8; 5.7] in the no remote consultation group (p < 0.01). In this large prospective cohort, we observed that the rate of weight loss was reduced during LD. This reduction was counterbalanced in participants involved in a remote consultation follow-up with a dose-effect response based on the number of remote consultations.

Highlights

  • The COVID-19 pandemic has forced countries around the world to develop various strategies to slow down and contain the spread of the SARS-CoV-2

  • The number of remote consultations did not have a significant impact on the decrease in waist circumference (p = 0.51). In this large prospective cohort of individuals undergoing a weight loss program, we found that the rate of weight loss was reduced during LD compared to before and after

  • There was a decrease in the weight loss trajectory during LD, we found that participants included in the RNPC® program continued to demonstrate a median decrease of 2.4 kg [0.5; 6.4] and a median decrease in waist circumference of 2 cm [; 6]

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Summary

Introduction

The COVID-19 pandemic has forced countries around the world to develop various strategies to slow down and contain the spread of the SARS-CoV-2. There was a decrease in physical activity levels, an increase in sedentary time associated with an alteration of eating behaviors [4], and an objectively measured reduction in the number of steps per day of up to a 50% [3]. Social isolation has the potential to worsen lifestyle behaviors by increasing sedentary time, decreasing outdoor time and physical activity, which in turn favors weight gain [8]. Such lifestyle modifications (eating habits and physical activity levels) were exacerbated in people with obesity [9,10]

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