The impact of state cannabis legislation, county-level socioeconomic and dog-level characteristics on reported cannabis poisonings of companion dogs in the USA (2009-2014).

Mohammad Howard-Azzeh,David L Pearl,Roksolana Hovdey,Terri L O’Sullivan,Alexandra Swirski,Olaf Berke,Madeline Ward,Simon Clegg

doi:10.1371/journal.pone.0250323

Mohammad Howard-Azzeh, David L Pearl + Show 6 more

Open Access

https://doi.org/10.1371/journal.pone.0250323

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Journal: PloS one	Publication Date: Apr 16, 2021
Citations: 10	License type: CC BY 4.0

Affiliation: University of Guelph

Abstract

With current trends in cannabis legalization, large efforts are being made to understand the effects of less restricted legislation on human consumption, health, and abuse of these products. Little is known about the effects of cannabis legalization and increased cannabis use on vulnerable populations, such as dogs. The objective of this study was to examine the effects of different state-level cannabis legislation, county-level socioeconomic factors, and dog-level characteristics on dog cannabis poisoning reports to an animal poison control center (APCC). Data were obtained concerning reports of dog poisoning events, county characteristics, and state cannabis legislation from the American Society for the Prevention of Cruelty to Animals’ (ASPCA) APCC, the US Census Bureau, and various public policy-oriented and government websites, respectively. A multilevel logistic regression model with random intercepts for county and state was fitted to investigate the associations between the odds of a call to the APCC being related to a dog being poisoned by a cannabis product and the following types of variables: dog characteristics, county-level socioeconomic characteristics, and the type of state-level cannabis legislation. There were significantly higher odds of a call being related to cannabis in states with lower penalties for cannabis use and possession. The odds of these calls were higher in counties with higher income variability, higher percentage of urban population, and among smaller, male, and intact dogs. These calls increased throughout the study period (2009–2014). Reporting of cannabis poisonings were more likely to come from veterinarians than dog owners. Reported dog poisonings due to cannabis appear to be influenced by dog-level and community-level factors. This study may increase awareness to the public, public health, and veterinary communities of the effects of recreational drug use on dog populations. This study highlights the need to educate dog owners about safeguarding cannabis products from vulnerable populations.

Highlights

The lethality of cannabis on dogs is poorly understood [1] and there is no established minimum lethal dose (MLD) or median lethal dose (LD50) [2]
The majority of calls to the animal poison control center (APCC) were made by dog owners and most calls concerned neutered dogs (Table 2)
By identifying dog and community-level characteristics that impact cannabis calls to the APCC, this study adds to the growing One Health discourse concerning the connected health of humans and animals

Summary

Introduction

The lethality of cannabis on dogs is poorly understood [1] and there is no established minimum lethal dose (MLD) or median lethal dose (LD50) [2]. Several studies have examined the impact of legalized cannabis possession on human populations [14,15,16,17], more research is needed [18]. Previous studies have noted a positive association between dog owners’ medical cannabis licenses and cannabis toxicosis in dogs [21], as well as an increase in accidental exposure to cannabis products in dogs [3]. These reports support the concern that legislation may impact the risk of cannabis poisoning events in dogs. No study has examined the impact of cannabis legislation on dogs

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