Abstract
Feed additives are used frequently in variable combinations to maximize broiler productivity and consumer safety. Therefore, we evaluated the efficiency of feed additives used in four different diets: a basal diet, a probiotic (PRO-PAC®) supplement diet, an egg yolk purified immunoglobulin Y (IgY) supplemented diet, and a combination of IgY and PRO-PAC® supplement (n = 15 for each group). We assessed the improvement of behavioral and hematological parameters of Ross broilers before and after an immune stress challenge using lipopolysaccharide (LPS). Behavioral as well as physiological parameters were analyzed. The standing frequency was the highest (P < 0.05) in broilers supplemented with a combination of probiotics and IgY. Likewise, latency approach score to a novel object improved (P < 0.01) in the combination group at week-3. After intraperitoneal injection of LPS, this combination group achieved the best gait score at week-3, followed by week-5, compared to birds fed the basal diet. The heterophil/lymphocyte (H/L) ratio, heterophil differential count, and eosinophil differential count in the basal diet group that was challenged with LPS were significantly increased (P < 0.01, P < 0.001, P < 0.05, respectively) compared to the combination groups. Therefore, we concluded that the combination of IgY and probiotics can significantly improve the behavior and the underlying physiological parameters of Ross broilers. Consequently, this combination can improve the broilers′ health, welfare and produce a safe meat free from harmful chemical residues.
Highlights
The high demand for poultry meat promotes intensive growth of poultry production
The use of hen’s egg yolk immunoglobulin Y (IgY) as a feed additive has numerous advantages that involve (i) making of preferential use of chicken products, (ii) addressing the global challenge of microbial drug-resistant through reduction of antibiotic usage in the livestock industry, (iii) stimulation of immunogenicity against conserved mammalian proteins, which exists in birds due to their phylogenetic distance [10], which allows laying hens to be more efficient generators of antibodies against conserved epitopes compared to other animals, and (iv) providing passive vaccination against some bacterial infections, including Salmonellosis, Campylobacteriosis, Staphylococcus aureus, Streptococcus suis, and Brucella spp
The RBC counts from the control group that was challenged with LPS were the highest (212 ± 10.58), and the counts from the IgY-supplemented group that was challenged with LPS were the lowest (180 ± 6.92)
Summary
The high demand for poultry meat promotes intensive growth of poultry production. this intensive production has always been challenged by numerous obstacles such as physical, environmental, and medical stressors [1]. The use of hen’s egg yolk IgY as a feed additive has numerous advantages that involve (i) making of preferential use of chicken products, (ii) addressing the global challenge of microbial drug-resistant through reduction of antibiotic usage in the livestock industry, (iii) stimulation of immunogenicity against conserved mammalian proteins, which exists in birds due to their phylogenetic distance [10], which allows laying hens to be more efficient generators of antibodies against conserved epitopes compared to other animals, and (iv) providing passive vaccination against some bacterial infections, including Salmonellosis, Campylobacteriosis, Staphylococcus aureus, Streptococcus suis, and Brucella spp. This study was performed to investigate the effect of natural feed additives (IgY, probiotics, and a mixture of both), on promoting behavioral activities, health status, and immunity in broilers exposed to LPS
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
