Abstract
About 20% of the causes of infertility are genetic. Preimplantation genetic testing (PGT) is an early form of prenatal diagnosis that aims to prevent genetic diseases through embryo selection. Due to the complex nature of a follow-up in genetics the involvement of a multiprofessional healthcare team is needed, with a prominent role of the psychological support. There is an inverse relationship between mental health and infertility, with general well-being impairment. Most patients undergoing PGT may have experienced miscarriages, to have a children affected by genetic disease, themselves to be affected by a genetic disease, and/or have experienced previous in vitro fertilization (IVF) treatment failures, which can increase the level of negative affects and impact on quality of life. Therefore, couples referred to PGT are considered vulnerable due to the impact on mental and social health. Here we aimed to identify and compare the levels of affection and quality of life in patients undergoing IVF treatments with and without indication for PGT.
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