Abstract

The perinatal risk factors of transient hypothyroxinemia(TH) in premature very-low-birth-weight infants (VLBWI) was investigated by longitudinally assessing thyroid hormones concentrations during their early life after birth and analyzing the relationship to perinatal factors. The serum TT4 concentration on day 7 was (61.03±24.19)nmol/L and the incidence of TH was 12. 05% (n= 10). Pulmonary surfactant support ( OR = 14.25, 95% CI2. 61-70. 07), ventilation support ( OR = 13. 76,95% CI 2. 55-68. 05) , dopamine support ( OR = 9.45, 95% CI 2. 26-39. 5 ) , and gestational age less than 30 weeks ( OR = 5. 78,95% CI 1. 36-24. 49) were perinatal risk factors for TH of premature VLBWI. Key words: Thyroxine; Prematurity; Very-low-birth-weight infant; Hypothyroidism

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