Abstract
AIMS and MethodThis study aimed to compare the subjective quality of life and attitudes to medication between groups of patients with schizophrenia taking either olanzapine or traditional antipsychotic medication.ResultsThe two groups were matched for age, gender, length of illness and antipsychotic group demonstrated more extrapyramidal side-effects (EPS) and akathisia. Within this group, those with EPS scored lower on the affect balance scale of the Lancashire Quality of Life Scale than those without. More patients in the olanzapine group reported that medication was taken to prevent symptoms returning.Clinical ImplicationsThese results lend support to the hypothesis that the presence of EPS impairs quality of life and suggest that olanzapine therapy may improve patients' attitudes to medication.
Highlights
ConclusionThe concept of local as opposed to out of area admissions is an intuitively appealing one
The two groups were matched for age, gender, length of illness and antipsychotic group demonstrated more extrapyramidal side-effects (EPS) and akathisia
Poor rates of compliance are a problem for the treatment of schizophrenia and have been estimated to be between 11% and 80% (Kane, 1989)
Summary
The concept of local as opposed to out of area admissions is an intuitively appealing one. It broadly reflects the way English services are structured, and has evident relevance as a marker of service quality. It will be principally useful for local year to year comparison
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