The Impact of Nocturia Was Not Noted On Quality of Life After Renal Transplantation.

Abstract

Objective Nocturia is associated with impaired health and deterioration of sleep as well as deterioration of quality of life (QOL). However, the relationship between nocturia and QOL, sleep have not investigated in patients who underwent RTx. Therefore, we investigated the relationship between nocturia and their impact on QOL, sleep in patients with RTx. Patients and Methods This study included 40 patients who underwent RTx from DCD donors between October 1990 and April 2013 at our institute. Median age of the patients was 47 years (range, 26 to 63), and 70% were male. Median period of the dialysis before RTx was 154 months (13 to 252). Median time after RTx was 209 months (81 to 311). They were stratified into 2 groups: 20 patients needed to void 2 times and less (Gp1) and 20 patients needed to void 3 times and more at night (Gp2). QOL index, Athens Insomnia scale (AIS) and King's Health Questionnaire (KHQ) were used for the assessment of nocturia related QOL. Results Median age of the patients at RTx and period of the dialysis before RTx were significantly lower in Gp1 (41.4 years in Gp1 vs 49.8 years in Gp2, p=0.0018 and 95 months vs 171 months, p<0.0001), respectively. Median time after RTx was significantly longer in Gp1 (225 months vs 167 months, p=0.0213). Median nocturnal urine volume was significantly lower in Gp1 (871ml vs 1472 ml, p<0.001). Median brain natriuretic peptide (BNP) was significantly lower in Gp1 (22.5 pg/ml vs 68.1 pg/ml, p=0.019).Table: No Caption available.However, QOL index, AIS and KHQ were not significantly different.Table: No Caption available.Conclusion Nocturia in patients with RTx was caused by nocturnal polyuria. Nocturia did not affected QOL and sleep in RTx paitients.