The Impact of Human Immunodeficiency Virus Exposure on Respiratory Syncytial Virus-associated Severe Respiratory Illness in South African Infants, 2011-2016.

Meredith L Mcmorrow,Sibongile Walaza,Fathima Naby,Arthemon Nguweneza,Marietjie Venter,Orienka Hellferscee,Johanna M Mcanerney,Jocelyn Moyes,Nicole Wolter,Anne Von Gottberg,Marthi Pretorius,Florette K Treurnicht,Omphile Mekgoe,Cheryl Cohen,Shabir A Madhi,Stefano Tempia,Adam L Cohen

doi:10.1093/cid/ciz288

The Impact of Human Immunodeficiency Virus Exposure on Respiratory Syncytial Virus-associated Severe Respiratory Illness in South African Infants, 2011-2016.

Meredith L Mcmorrow, Sibongile Walaza + Show 15 more

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https://doi.org/10.1093/cid/ciz288

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Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America	Publication Date: Apr 9, 2019
Citations: 3

Affiliation: National Health Laboratory Service, University of KwaZulu-Natal, University of Pretoria, University of the Witwatersrand, Novartis (Switzerland), United States Public Health Service, Centers for Disease Control and Prevention, Respiratory and Meningeal Pathogens Research Unit, National Research Foundation, World Health Organization

#Respiratory Illness In Infants #Illness In Infants + Show 8 more

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Abstract

From 2011 through 2016, we conducted surveillance for severe respiratory illness in infants. Human immunodeficiency virus exposure significantly increased the risk of respiratory syncytial virus (RSV)-associated hospitalization in infants aged <5 months. More than 60% of RSV-associated hospitalizations occurred in the first 4 months of life and may be preventable through maternal vaccination or birth-dose monoclonal antibody.

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