Abstract
The German Consensus for matching allogeneic donors of hematopoietic progenitor cell (1996/2000) recommends matching donors for HLA-A,B on serological level (2 digit allele level matching within split groups for B15, B40) and by allele level for DRB1 and, if possible, DQB1. We have retrospectively performed sequencing based HLA-A,B,C analyses for 262 adult unrelated donor recipient pairs matching for A, B, and DRB1 according to the above definition in order to see if outcome could be improved by more stringent selection criteria.
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