THE IMPACT OF HIGH AND LOW FODMAP CONDITIONS ON BLOOD GLUCOSE CONCENTRATIONS IN HEALTHY YOUNG ADULTS

Abstract

Objective: Fermentable oligosaccharides, disaccharides, monosaccharides and polyols (FODMAPs) are a group of carbohydrates that evade digestion in the small intestine and are subsequently metabolized by colonic microbiota. Colonic fermentation of FODMAPs has been linked to a prebiotic effect resulting in improved blood glucose response and subjective appetite. The purpose of this study was to examine how changes in FODMAP consumption effects blood glucose response and subjective appetite. Fasting breath hydrogen was also examined as an indicator of colonic fermentation. Design: This study utilized a single blind, randomized, crossover design. Healthy participants (n=16) were instructed to follow a low-FODMAP and high-FODMAP diet for a period of three days separated by an 11-day “washout period.” Fasting and post-prandial blood glucose were assessed via Cholestech. Subjective appetite was analyzed through use of visual analogue scales. Data were analyzed via repeated measures analysis of variance. Results: Blood glucose concentrations did not vary significantly between the two dietary interventions (p=.111, η =.155). Reduced total area under the curve (TAUC)