Abstract

Introduction: Four randomised trials have shown that dose escalated prostate radiotherapy (DEPRT) improves tumour related outcomes, using additional fractions (3 photons, 1 proton) to deliver the boost (additional dose 11–15.6%). Two of the three trials performing a subgroup analysis did not show an advantage in their low-risk group patients. The aim of this study was to estimate the additional number of fractions required to implement DEPRT locally.

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