The impact of dental treatment on the salivary cortisol levels of children with severe early childhood caries.

Abstract

To compare salivary cortisol levels of caries-free children with those of children with severe early childhood caries (S-ECC) before and 3months after comprehensive dental treatment. Thirty children with S-ECC were matched with 30 caries-free children from middle income families with college-educated working mothers. Early-morning saliva samples were collected from the children using the passive drool method. Post-treatment saliva samples were collected 3months after completion of treatment in the S-ECC group. Salivary cortisol levels were analysed using electrochemiluminescence immunoassay. Salivary cortisol levels of caries-free children were significantly lower than both the pre-treatment and post-treatment levels of children with S-ECC (F=26.221, p<0.0001). The pre-treatment cortisol levels of children with S-ECC were significantly higher than the post-treatment levels (t=2.588, p=0.015). No significant differences in cortisol levels were observed between genders or between children treated over multiple visits under local analgesia and in a single visit under general anaesthesia. Dental treatment significantly reduced the salivary cortisol levels of children with S-ECC, however, the post-treatment levels remained significantly higher than those of caries-free children.