The impact of comorbidities and age on the nosocomial outcomes of patients undergoing coronary artery bypass grafting

Abstract

Aim. To assess the incidence of unfavorable in-hospital outcomes (fatal and non-fatal complications) following coronary artery bypass grafting (CABG), depending on the age of the patient and the presence of comorbidities. Material and methods . In the period from 2011 to 2012 we included in the study 680 patients for elective CABG (single-site, register, prospective study). Combined clinical endpoint (CCE) included the presence of myocardial infarction (MI), multiple organ dysfunction syndrome (MODS), heart failure (HF), new atrial fibrillation (AF) after CABG, repeat mediastinotomy (of one or more complications) and/or deaths. Results. There is a high prevalence of comorbidities among the patients referred to CABG. One hundred fifty two (22,40%) patients reached the CCEs. The highest rate of the CCEs was recorded in the group of patients undergoing concomitant CABG, compared to the group of patients after isolated CABG. Patients’ age was associated with the development of CCE in the early postoperative period. The highest number of CCEs was registered in the group of patients with combined surgical interventions. Conclusion . Factors associated with the probable development of unfavorable nosocomial outcomes either fatal or non-fatal following is the age of patients 61 years and older, concomitant CABG, and the extracorporeal circulation.