Abstract
Objective: The objectives of this study include performing pharmaceutical care-related research and documenting regarding drug-related problems in the surgery department. Further, these types of studies may bring consciousness to both physicians and patients regarding drug use in surgery.
 Methods: A Prospective interventional study was conducted in a general surgery hospital. The prescriptions were analyzed for the use of inappropriateness of drugs using the classification for drug-related problems.
 Results: Out of 100 cases, 62 patients were observed with drug-related problems. The number of antibiotics prescribed was 0, 1, 2, 3, 4, 5, 6 in 8, 11, 12, 32, 18, 18, 1 cases respectively. A significant increase in the outcome of antibiotic rationality and cases adhered to guidelines was seen in November compared to October and somewhat decreased in December due to some limitations. The overall study states that prescribing has a more important cause of Drug-related problems compared to dispensing and the use of the drug.
 Conclusion: Drug-related problems have to be acknowledged as a very important contributing treatment factor for the best health care outcome. Our study shows the importance of clinical pharmacists in every hospital for identifying and resolving drug-related problems and medication errors.
Highlights
Medications play a major role in cure palliation and inhibition of disease; they expose patients to Drug-Related Problems (DRPs) [1]
In December out of 24 cases rationality were followed in 13 cases, not followed were 11, cases adhered to guidelines were 12 and cases without DRPs were 10. and fig. 1 explains that in the month of October 50 % of cases followed antibiotic rationality and 32.50% of cases adhered to guidelines out of 40 cases
The study states that DRPs caused due to improper drug selection were found to be highest which accounts for 22.17% and an acceptance rate of clinical pharmacist recommendations is 62.8% and change in drug therapy was found to be low.1.68% were neither accepted nor the therapy was changed, [4] but in our study shows that DRPs caused due to improper drug selection accounts for 54% and all the interventions made are accepted
Summary
Medications play a major role in cure palliation and inhibition of disease; they expose patients to Drug-Related Problems (DRPs) [1]. An actual problem has related to clinical manifestations like Adverse Drug Reactions or Therapy failure due to incorrect dosage. In India many factors contribute to DRPs, of these factors related to health care providers are misuse medications in prescribing practices, time constraints, diagnostic uncertainty, poor availability of laboratories. The main need is to enhance the role of clinical pharmacy services in the hospital which influences the patient's health care in a positive outcome. The main aim of this study is to perform pharmaceutical care-related research and document regarding medical errors and drug-related problems in surgery. These types of studies may bring consciousness to both physicians and patients regarding drug use in surgery
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