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Abstract
Background The management of multiple long-term medicines of patients with chronic diseases creates a burden for patients. However, limited research is performed on its impact on patients’ daily lives. Objective The aim of this study was to explore the impact of cardiovascular medication on different daily life aspects and to examine differences of these aspects between adherent and non-adherent patients. Setting Two community pharmacies in the Netherlands. Method In this cross-sectional study patients (≥ 45 years) using cardiovascular medication participated. Two equally group sized samples of patients non-adherent as assessed with pharmacy refill data, and patients adherent were selected. Main outcome measure Data were collected by means of the Living with Medicines Questionnaire measuring the impact of medicines use on patients’ daily lives. Results In total, 196 patients participated, including 96 non-adherent patients. Substantial proportions of patients experienced medication-related burden on different daily life aspects. This burden was mainly related to the acceptance of long-term medicine use, medication-related concerns or dissatisfaction, the interference of medicines with social and daily lives, and the interaction and communication with health care providers. No statistically significant results were found when comparing the impact on patients’ daily lives between adherent and nonadherent patients. Conclusion Health care providers should acknowledge the impact of multiple long-term medicines on patient’s daily lives and should make an effort to diminish patients’ medication-related burden by improving patient–provider relationships and by providing adequate treatment information incorporating patients’ individual circumstances. This may facilitate the integration of long-term medicine use in patients’ daily lives.
Highlights
MethodPatients with chronic diseases are confronted with developing an understanding of the disease and treatment, should attend regular appointments, take several chronic medicines and enact lifestyle changes [1,2,3,4,5]
No significant differences in patient characteristics between the adherent and non-adherent sample were found, except for number of prescribed medicines
More non-adherent patients used more than four prescribed medicines (p = 0.004) than adherent patients
Summary
MethodPatients with chronic diseases are confronted with developing an understanding of the disease and treatment, should attend regular appointments, take several chronic medicines and enact lifestyle changes [1,2,3,4,5]. Excessive medication-related burden may increase the negative impact on patients’ daily lives and negatively affects the health-related quality of life [7, 8]. This is especially the case in patients with cardiovascular disease for whom mostly multiple medicines are prescribed and for whom most medicines prescribed must be used until the end of their life [1, 2]. Limited data on patients’ experienced burden of long-term medicine use and its impact on patients’ daily lives especially in cardiovascular disease are available. The management of multiple long-term medicines of patients with chronic diseases creates a burden for patients. Limited research is performed on its impact on patients’ daily lives
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