Abstract
Plain Language SummaryThe mortality rate of critically ill patients with severe acute kidney injury (AKI) requiring continuous renal replacement therapy (CRRT) remains high. In addition, predicting the prognosis of these patients, which is crucial for determining the appropriate treatment level and timing, is difficult. Herein, we evaluated the C-reactive protein-to-albumin ratio (CAR) as a prognostic factor and compared its predictive performance with those of traditional severity scores. Our study demonstrated that high CAR was associated with increased in-hospital mortality. In particular, the addition of CAR to the APACHE II and SOFA scores was superior to traditional severity scores alone in predicting mortality. Consequently, CAR can be used to enhance the accuracy of predicting mortality in patients with severe AKI who require CRRT.
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