Abstract
Chronic diseases and their treatment regimen plays a greater role in determining the patient related health outcomes of which one is Health Related Quality of Life. Hypertension itself along with its pharmacotherapy impacts HRQoL of hypertensive patients. The primary objective of the study was to determine the impact of f hypertensive medications on the health-related quality of life among hypertensive patients with the secondary objective to assess which medication significantly affects health related quality of life of hypertensive patients. A quantitative questionnaire based cross-sectional survey was undertaken in outpatient departments of Sandeman Provisional Hospital (SPH) Quetta using an EQ-5D-3L to determine the Health-Related Quality of Life. Convenience Sampling technique was used for data collection. Majority of respondents (8.7%) had no problem in first three domains while having some problem in pain and anxiety domains. Following them 7.6% of patients had some problems in all domains of the EQ5D tool. Moreover. the ACE Inhibitors and Diuretics impacts HRQoL of patients of current study. A total of 263 participated in the study of which (25%) of the respondents were of age group 48 -75 years old and were married 73.4% mostly. Majority (8.7%) had no problem in first three domains while having some problem in pain and anxiety domains. ACE Inhibitors and Diuretics significantly influence the health status of hypertensive patients acquiring pharmacotherapy. It was concluded that antihypertensive agents have a significant impact on HRQoL of hypertensive patients especially Angiotensin Converting Enzymes and Diuretics, which show significant impact on HRQoL of hypertensive patients. However, it is also suggested to assess the impact of antihypertensive therapies given in combination must also be studied in order to provide health professionals a better understanding of their prescribed regimen to improve patient related health outcomes.
Highlights
Hypertension is a continuing health problem of immense public health concern globally especially for developing world [1]
It was concluded that antihypertensive agents have a significant impact on Health-related quality of life" (HRQoL) of hypertensive patients especially Angiotensin Converting Enzymes and Diuretics, which show significant impact on HRQoL of hypertensive patients
It is suggested to assess the impact of antihypertensive therapies given in combination must be studied in order to provide health professionals a better understanding of their prescribed regimen to improve patient related health outcomes
Summary
Hypertension is a continuing health problem of immense public health concern globally especially for developing world [1]. In 2010, 1.39 billion individuals globally were living with increased blood pressure, and out of those, 1.04 billion were from Lower Middle-Income Countries and 349 million in Higher Income Countries [2]. It was projected that in the year 2025, the number may increase to 60% to a total of 1.56 billion [3]. Half of the total death toll caused by stroke and heart disease is due to hypertension. It is the most important risk factor for cardiovascular diseases [3]. Pharmacological and nonpharmacological, have been designed for the purpose of treating hypertension.
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