Abstract
Purpose: The purpose of the study is to evaluate the analgesic effect of adding magnesium sulfate to bupivacaine in Fascia Iliaca Compartment Block (FI-CB). Patients and Methods: Ninety-six burn patients scheduled for skin-grafting procedures were allocated into two equal groups. After induction of general anaethesia, forty-eight patients received US guided FICB using 35 ml bupivacaine 0.25% + 5 ml isotonic sodium chloride solution with a total volume of 40 ml. The other forty-eight patients received 35 ml bupivacaine 0.25% + 250 mg of magnesium sulfate with a total volume of 40 ml. Results: Total postoperative pethidine consumption in the first 24 h post-operative showed a highly statistically significant decrease in the magnesium group in comparison to the bupivacaine group. Conclusion: Adding magnesium sulfate to bupivacaine in FICB in skin grafting procedures decreased the pain scores post-operative, delayed the first request of analgesia and reduced the total analgesic consumption in the first 24 h post-operative without any significant side effects.
Highlights
Patients who survive severe burns undergo multiple reconstructive surgeries to re-establish function
SPSS’ chart builder and Microsoft Excel for windows 2019 were used for generating charts. This double blind prospective randomized controlled study was conducted on 96 patients ASA I, II of either sex between 21 and 60 years who were scheduled for skin grafting procedures for treatment of second- or third-degree burn
These findings are consistent with Muthiah et al, who proved that adding 150 mg magnesium to bupivacaine in 3-in-1 nerve block had no effect on intraoperative hemodynamics [12]
Summary
Patients who survive severe burns undergo multiple reconstructive surgeries to re-establish function. These operations involve placement of split-thickness skin. Regional nerve blockade has been used to provide better analgesia [2]. Skin graft donor sites are usually chosen from the lateral and/or anterior upper part of the thigh. These areas coincide with the distribution of the lateral femoral cutaneous nerve (LFCN) and femoral nerve [3]. The fascia iliaca compartment block (FICB) is effective in producing the simultaneous blockade of both LFCN and femoral nerve [4]. The local anesthetics (LA) should spread between the iliacus muscle and the fascia iliaca [5]
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