The impact of a multi-fruit wine on serum urea, albumin and total tissue protein levels in rats

Abstract

This present research is aimed at evaluating the impact of a multi-fruit wine obtained from a blend of five fruits on serum urea, albumin and total tissue protein in albino Wistar rats. Seventy (70) albino Wistar rats were randomly divided into seven (7) study groups of ten rats per group (n=10). The animals were placed on either low (corresponding to four standard drinks) or high (six standard drinks) doses of multi-fruit wine with additives (MFWA) or plain wine (MFWP), low doses of red wine or cashew wine. All animals had free access to normal rat feed and drinking water. The feeding regimens lasted for 2 weeks. The result showed no significant difference (p≥0.05) in serum urea, protein homogenate and supernatant tissue protein among groups administered the multi-fruit wine. High dose of multi-fruit wine plain (H-MFWP) and low dose of red wine (STD 1) increased serum albumin concentrations significantly (p<0.05) compared with the control. Results of the investigation showed no adverse alteration in the biochemical parameters of the experimental animals following administration of the multi-fruit wine, suggesting that the multi-fruit wine can be used alongside other therapeutic purposes associated with the maintenance of the kidney and liver function.