Abstract
Pigs given multiple infections of third stage Hyostrongylus ribidus larvae over a 10-day period produced detectable circulating agglutinins 2–3 days after the initial infection. Titres were neither higher nor more prolonged than those of pigs which received a single infection of larvae, although fluctuations in titres over a 30-day period were more marked. Pigs reinfected with a single dose of third stage larvae, however, showed a rapid initial decline in titre followed by a gradual increase to a level higher than that detected at primary infection. Biological manifestations of immunity such as a decreased parasite egg output and increased prepatent period were also seen. The host reaction to reinfection is regarded as an anamnestic response.
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