Abstract
Purpose: Peripheral and central senzitization are two of the underlying mechanisms of pain in patients with knee osteoarthritis (KOA). From the quantitative sensory testing procedures, pain pressure threshold (PPT) measurement is a commonly used method for investigating the magnitude of peripheral and central senzitization in patients with KOA. Out of several interventions, manual mobilization has been proven to be effective in increase of PPT in patients with KOA. The effectiveness of Maitland mobilization in increase of pain threshold has also been shown in patients with KOA; however, the effect of end-range Maitland mobilization has not been studied yet.
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