Abstract

The absorption of nutrients in the small intestine depends on both the efficiency of the epithelial transport mechanisms and the length of time that nutrients remain in contact with the absorptive epithelium [1, 2]. The existence of neurohumoral mechanisms controlling either of these functions has never been established. The aim of the present study was to investigate the possible existence of a feedback mechanism, whereby the presence of nutrients in the distal small intestine might control small intestinal transit, allowing optimal time for absorption to occur.

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