Abstract
Fallopian tube cilia (FTC) play an important role in female infertility but have not been comprehensively explored. This review screened 141 tubal cilia-related papers to reveal the detection techniques of FTC function and morphology and the related analysis of female infertility and other gynaecological disorders in FTC.FTCs differentiate from progenitor cells and develop into primary and motile cilia. Primary cilia coordinate multiple signaling pathways; motile cilia produce laminar flow through bidirectional intraflagellar transport (IFT), which drives the movement of oocytes and gametes. Several methods for quantitative detection and protein analysis were used to better explore the factors contributing to the decrease in ciliary beat frequency (CBF) and the cellular mechanism of ciliary cell death and shedding. Changes in cilia number, cilia structure and CBF were observed in both primary and secondary ciliary lesions affected by reproductive diseases, and disturbances in the ciliary signaling pathway led to abnormal laminar flow and decreased cilia pickup and transport.
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