Abstract

6,15-Dioxo-PGF 1α, 6-15-dioxo-13,14-dihydro-PGF 1α and 15-oxo-thromboxane B 2 have been identified in incubates of ram seminal vesicle homogenates with added arachidonic acid or in the perfusate from sensitised challenged guinea pig lungs. These compounds are probably related to 6-oxo-PGF 1α and thromboxane B 2. The structures have been determined by gas chromatography mass spectrometry, following suitable chemical derivatisation.

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