Abstract
In 2006 I was working as a registrar in renal medicine at Hammersmith Hospital. One of my colleagues, Patrick Maxwell, was interested in investigating families in which multiple individuals had unexplained renal disease. He felt that hunting for the genes underlying their conditions was worthwhile, feasible and would make an excellent project for a clinical researcher: recent technical advances in genetics – principally the ability to genotype large numbers of markers across the genome relatively easily – have made linkage studies more widely accessible to researchers, so with Patrick Maxwell's help and supervision I embarked on the study of one such family.
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