The identification of cancer lesions in mammography images with missing pixels: analysis of morphology

Abstract

The quality of mammography images is essential for the diagnosis of breast cancer and image imputation has become a popular technique to overcome noise, artifacts, and missing data to aid in the diagnosis of diseases. In this paper, we assess the performance of six imputation methodologies for the reconstruction of missing pixels in different morphologies in mammography images. The images included in this study are collected from four public datasets (CBIS-DDSM, Mini-MIAS, INbreast, and CSAW) and the imputation results are evaluated through the mean absolute error (MAE) and structural similarity index measure (SSIM). This study goes beyond the traditional evaluation of imputation algorithms, analyzing imputation quality, morphology preservation and classification performance. The effects of imputation on the morphology of cancer lesions are of utmost importance since it lays the foundation for physicians to interpret and analyze the imputation results. The results show that DIP is the most promising methodology for higher missing pixel rates, morphology preservation, and classifying malignant and benign images.