Abstract
The Icatibant Outcome Survey (IOS; NCT01034969) monitors icatibant safety and effectiveness in a real-world setting. While icatibant is licensed in numerous countries for hereditary angioedema (HAE) attacks in adults with C1-INH deficiency, we report IOS data for off-label use in angioedema due to acquired C1-INH deficiency. This condition shares a mechanism and clinical profile with HAE, but is less prevalent.
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