Abstract

Comment on: (1) Proteasomal regulation of the hypoxic response modulates aging in C. elegans. Mehta R, Steinkraus KA, Sutphin GL, Ramos FJ, Shamieh LS, Huh A, Davis C, Chandler-Brown D, Kaeberlein M. Science;324:1196-8. (2) HIF-1 modulates dietary restriction-mediated lifespan extension via IRE-1 in Caenorhabditis elegans. Chen D, Thomas EL, Kapahi P. PLoS Genet 2009; 5:e1000486.

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