Abstract

Background: Mild cognitive impairment (MCI) is a stage preceding dementia, and early intervention is critical. This study investigated whether multi-domain cognitive training programs, especially robot-assisted training, conducted 12 times, twice a week for 6 weeks can improve cognitive function and depression decline in community-dwelling older adults with mild cognitive impairment (MCI). Methods: A randomized controlled trial was conducted with 135 volunteers without cognitive impairment aged 60 years old or older. Participants were first randomized into two groups. One group consisted of 90 participants who would receive cognitive training and 45 who would not receive any training (NI). The cognitive training group was randomly divided into two groups, 45 who received traditional cognitive training (TCT) and 45 who received robot-assisted cognitive training (RACT). The training for both groups consisted of a daily 60 min session, twice a week for six weeks. Results: RACT participants had significantly greater post-intervention improvement in cognitive function (t = 4.707, p < 0.001), memory (t = −2.282, p = 0.007), executive function (t = 4.610, p < 0.001), and depression (t = −3.307, p = 0.004). TCT participants had greater post-intervention improvement in memory (t = −6.671, p < 0.001) and executive function (t = 5.393, p < 0.001). Conclusions: A 6-week robot-assisted, multi-domain cognitive training program can improve the efficiency of global cognitive function and depression during cognitive tasks in older adults with MCI, which is associated with improvements in memory and executive function.

Highlights

  • Demographic Changes and Mild Cognitive ImpairmentMild cognitive impairment (MCI) is a stage preceding dementia that does not meet the dementia criteria but leads the affected individual to show reduced cognitive function in such domains as memory and language in comparison with healthy individuals of the same age group and with similar levels of education; MCI individuals may show normal or slightly reduced daily activities [1]

  • The findings are of considerable significance in that the effects of the robot-assisted cognitive training (RACT) program on the cognitive functions and depression in MCI elders were evaluated through comparisons involving three groups, between RACT and not receive any training (NI) as well as between RACT and traditional cognitive training (TCT)

  • In contrast with the NI group, the participants in the RACT and TCT groups showed an improvement in cognitive functions, while the effect of the program on depression was greater in RACT than TCT after the intervention

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Summary

Introduction

Demographic Changes and Mild Cognitive ImpairmentMild cognitive impairment (MCI) is a stage preceding dementia that does not meet the dementia criteria but leads the affected individual to show reduced cognitive function in such domains as memory and language in comparison with healthy individuals of the same age group and with similar levels of education; MCI individuals may show normal or slightly reduced daily activities [1]. Mild cognitive impairment (MCI) is a stage preceding dementia, and early intervention is critical. This study investigated whether multi-domain cognitive training programs, especially robot-assisted training, conducted 12 times, twice a week for 6 weeks can improve cognitive function and depression decline in community-dwelling older adults with mild cognitive impairment (MCI). Results: RACT participants had significantly greater post-intervention improvement in cognitive function (t = 4.707, p < 0.001), memory (t = −2.282, p = 0.007), executive function (t = 4.610, p < 0.001), and depression (t = −3.307, p = 0.004). Conclusions: A 6-week robot-assisted, multi-domain cognitive training program can improve the efficiency of global cognitive function and depression during cognitive tasks in older adults with MCI, which is associated with improvements in memory and executive function

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