The human body burden of polychlorinated biphenyls in serum of residents in an area from Hubei Province

Abstract

Concentrations of dioxin-like polychlorinated biphenyls (dl-PCBs) and non-dioxin-like PCBs (ndl-PCBs) in 26 serum samples of the residents from Hubei Province were analyzed via high-resolution gas chromatograph tandem high-resolution mass spectrometer (HRGC-HRMS) method. Total concentrations of twelve dl-PCBs (Σdl-PCBs) were in range of 366.30-4 945.77 pg/g fat, with the mean value (2 093.76 pg/g fat), and PCB 118 was the predominant congener. For six ndl-PCBs, total concentrations (Σndl-PCBs) were in range of 2 671.32-20 626.26 pg/g fat (mean 12 505.45 pg/g fat), and PCB 153 was the predominant congener. Mean concentration of Σdl-PCBs were significantly and positively associated with age (rs=0.574, P=0.002). The mean World Health Organization toxicity equivalent (WHO-TEQ) of dl-PCBs (ΣTEQdl-PCBs) were range from 0.07 to 8.69 pg/g fat.