The hormonal indices of hypophysis-adrenal glands system in combatants during missions to "trouble spots".

Abstract

The officials of the Interior Ministry of Russia usually perform their duties in extreme and quite often emergency conditions. The hypophysis-adrenal glands system of regulation mainly contributes into supporting formation of mechanisms of compensation of these exposures. The purpose of study is to analyze alterations of content of adrenocorticotropic hormone, cortisol, adrenaline and noradrenaline in officials of the Interior Ministry sent on a mission to territories with local military conflict (the Northern Caucasus) to support public order. The study results demonstrated that during first two months of mission a significant increasing of level of analyzed hormones occurs. This is a proper reaction to changed conditions of environment. These alterations correspond to main propositions of the general adaptation syndrome theory. However, further observation in dynamics of mission established presence of signs of imbalance of secretion of hormones in hypophysis-adrenal glands system. The long-lasting conserving high content of both of adrenocorticotropic hormone and cortisol till the end of mission was established. At the same time, content of hormones of "fast response" to extreme factors of environment (adrenaline, noradrenaline) occurred to be as higher as at the beginning of mission. Such occurrences result in disorder of regulation of inter hormonal relationships that correspondingly is a factor of decreasing of vital stress resistance of organism. The main directions of organizational medical character are proposed within th framework of activities supporting resistance of organism to conditions of extreme impact of emergency situations and decreasing risk of development of pathological conditions.