Abstract

The history of the neglected tropical disease movement is seen through the lens of authors who worked during the last 4 decades in different roles and in different settings, from Western-based laboratories to clinical roles in endemic countries and in critical policy roles in the World Health Organization (WHO). The authors seek to identify key players from the introduction of the word ‘neglected’ by the late Kenneth Warren in his Rockefeller Foundation–supported Great Neglected Diseases of Mankind movement through to the more recent developments after the London Declaration of 2012. The role of the various actors—endemic countries, major pharmaceutical companies, the WHO, non-government development organizations, bilateral donors and academia—are discussed. The critical events and decisions are highlighted that were essential enabling factors in creating a viable and successful movement and with a resultant massive global public health and antipoverty impact. The importance of advocacy is emphasized in creating the momentum to establish a globally recognized public health ‘brand’ as a target in the United Nations Sustainable Development Goals.

Highlights

  • Estimates suggest that approximately 1 in 10 of the world’s population live in extreme poverty, with most infected with one or more of the neglected tropical diseases (NTDs)

  • In parallel with Warren’s initiative in 1976, the World Health Organization (WHO) Special Programme for Research and Training in Tropical Diseases (TDR) was established under the auspices of the World Bank and United Nations Development Programme (UNDP), a partnership of multilateral and bilateral donors and disease-endemic countries to study a similar portfolio of diseases under the successive leadership of Howard Goodman, Adetokundu Lucas and Tore Godal

  • The concept was pioneered by Frank Hawking during the 1950s and 1960s using diethylcarbamazine citrate (DEC) for lymphatic filariasis (LF)[7,8] and by the Chinese using DECfortified salt for filariasis control in a population of 350 million people.[9]

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Summary

The history of the neglected tropical disease movement

The history of the neglected tropical disease movement is seen through the lens of authors who worked during the last 4 decades in different roles and in different settings, from Western-based laboratories to clinical roles in endemic countries and in critical policy roles in the World Health Organization (WHO). The authors seek to identify key players from the introduction of the word ‘neglected’ by the late Kenneth Warren in his Rockefeller Foundation–supported Great Neglected Diseases of Mankind movement through to the more recent developments after the London Declaration of 2012. The critical events and decisions are highlighted that were essential enabling factors in creating a viable and successful movement and with a resultant massive global public health and antipoverty impact. The importance of advocacy is emphasized in creating the momentum to establish a globally recognized public health ‘brand’ as a target in the United Nations Sustainable Development Goals

Introduction
Transactions of the Royal Society of Tropical Medicine and Hygiene
The London Declaration
Findings
Future directions
Full Text
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