Abstract
Background: Meningiomas are slow-growing and benign tumor of the meninges, which line the skull and enclose the brain. Methods: We have studied 324 cases of meningeal lesions (clinically diagnosed and histologically proved) in Department of Pathology of a tertiary care hospital. We evaluated its frequency, age and sex distribution and documented as per the WHO histological grade of meningioma. Results: The commonest age group affected was 41-60 years. Female predominance was seen. Headache being most common symptom with commonest site was intracranial (88.2%). The meningeal lesions consisted of meningioma (96.6%) and non-meningioma lesions (3.4%). The commonest histopathological type of mengioma was transitional (24.2%) followed by meningotheliomatous (22.8%). The 85.6% of the meningioma was WHO Grade I tumor. For WHO Grade II meningiomas, mitotic figures and high cellularity was helpful to diagnose the tumors. The non-meningioma lesions included hemangiopericytoma, solitary fibrous tumor, malignant melanoma and metastasis by carcinoma breast, lung and thyroid. Conclusion: From our study, we can conclude that benign meningiomas WHO grade I are most common. Intracranial location is the most common for meningioma. Middle-aged group of 41–60 years was predominently affected and it is uncommon in children. Keywords: Meningeal neoplasms, Meningioma, WHO grade
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