THE HISTOLOGICAL SPECTRUM OF MENINGIOMAS

Abstract

Introduction: Meningiomas are a group of slow-growing, primary intracranial neoplasms, that account for approximately 28 to 30% of the primary central nervous system (CNS) tumors1,2,3,4. They can occur at any age but are most common in middle-aged patients1. Headache is the most common symptom followed by seizures in the cases of intracranial meningiomas. Accurate histopathological diagnosis and grading of these tumors are essential for the management, prognosis, and follow-up of patients. To study Aims and Objectives: incidence, histomorphological types and grade meningiomas according to the WHO grading system. It is a retrospe Material and methods: ctive study comprised of 46 cases of meningioma, which are diagnosed in the Pathology Department. In the present study, Result: the most common age group for presentation is 41-50 years. Male to Female ratio was 1:2.01. Among the chief presenting symptoms, headache is the most common symptom followed by seizures. Meningothelial meningioma was the most common subtype, followed by psammomatous meningioma. Meningiomas are rare slow- Conclusion: growing tumors which are more common in the adult female. A meningothelial variant is the most common variant which is WHO grade 1 meningioma, readily curable by resection. Grade 1 meningiomas have a good prognosis whereas grade 2 and 3 meningiomas have low frequency but come with a poor prognosis