The Hematopoietic Stem Cells Promise to Support Men more than Women

Abstract

Introduction. Haematological parameters such as haemoglobin, haematocrit and red blood cells are very important in determining health and physiological status of a human. It is perceived that the haematological parameters level can change depending on the person`s age and gender. We designed a study to investigate the differences among Persian males and females. Materials and Methods. Totally 2434 healthy people were selected randomly for this research. The Hgb, HCT and RBC amounts were recorded individually. Also, the colony-forming unit assay results of 32 622 newborns’ cord blood was investigated. Results. The outcome has shown that females have the lower haematological parameters amounts rather than males. The amounts of these parameters decrease in men over 35 years of age, but since females in their middle age have significant decline in Hgb, HCT and RBC values, their haematological parameters increase in their blood after middle age. Moreover, the colony assay results indicated that the myeloid progenitor in the cord blood of newborn boys is more than in newborn girls. Conclusion. In conclusion, the variation in haematological parameters in different genders throughout a person’s life is related to various factors such as hormonal changes and hematopoietic stem cells differentiation in cord blood. Key words: haematological parameters, haemoglobin, haematocrit, red blood cell, colony-forming unit assay, hematopoietic stem cells, cord blood, age, male, female