Abstract
A simple noninvasive technique for assessing baroreceptor responsiveness is described utilising the changes in heart rate to a modified Valsalva manoeuvre. The response is expressed in terms of a derived parameter called the heart-rate sensitivity, which is defined as the variation in heart rate (beats per minute) before and after the manoeuvre per unit change in arterial blood pressure (mm Hg). Fourteen normotensive subjects showed an average value of heart-rate sensitivity of 1·51 (s.d.=0·55) over a total of 154 manoeuvres, while another group of seven yielded values always less than one. Each subject of the latter group (except one) reported some cardiovascular characteristic with possible clinical relevance.
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