Abstract

The Grand Challenge for Frontiers in Genetics: To Understand Past, Present, and Future

Highlights

  • The latest waves of both data and methods to generate and understand them bring us ever increasing ability to understand our own past as a species and of that of life on our planet

  • Still many mysteries remain regarding our evolutionary history. Some of these go to the most fundamental questions about why it is advantageous for our species to reproduce sexually, to have only two sexes, to grow old and die, and to engage of certain forms of altruistic behavior (Hurst, 1996; Brooks, 2008; Nowak et al, 2010)

  • These are some of the most fascinating questions potentially permitting some of the most beautiful and elegant mathematical and biological explanations, some of which intrigue us because they go to the fundamental essence of who and what we are and where we have come from

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Summary

Introduction

The latest waves of both data and methods to generate and understand them bring us ever increasing ability to understand our own past as a species and of that of life on our planet. Some of these go to the most fundamental questions about why it is advantageous for our species to reproduce sexually, to have only two sexes, to grow old and die, and to engage of certain forms of altruistic behavior (Hurst, 1996; Brooks, 2008; Nowak et al, 2010). The first component of our grand challenge is to understand “what was,” using the tools given to us by modern genomics.

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