The grading diagnosis of the magnetic resonance imaging and magnetic resonance spectroscopy and gross motor rating scale for children with cerebral palsy

Abstract

Objective To investigate the grading diagnostic value of magnetic resonance spectroscopy and magnetic resonance imaging and gross motor rating scale for children with cerebral palsy. Methods Forty cases of healthy children under 1.0~2.0 years old and 42 cases of cerebral palsy children under 1.1~2.0 years old were enrolled in the study, and we compared the inspection reports on MRI and MRS statistical analysis.According to the results of MRI for dividing cerebral palsy, and MRS indexing of NAA/Cr, CHO/Cr, LAC/Cr levels were compared; different types of cerebral palsy by GMFM scores were examined. Results Nuclear magnetic resonance(MRI)and MRS could effectively distinguish typical pathological changes in the brain of children with cerebral palsy, the cerebral NAA, Cr, Cho could appear significant formant when the children detected by MRS, could be quantitatively detected with MRS.The levels of NAA/Cr、CHO/Cr、LAC/Cr of different MRS and MRI degree was different, and the difference of moderate CP and severe CP was significant(P<0.05). Compared with MRS, the accordant rates of the MRI was not ideal, But gross motor rating scale score suggested that there were differences between the cerebral palsy of the MRI and MRS degree(P<0.05). Conclusion The magnetic resonance imaging and magnetic resonance spectroscopy and gross motor rating scale can effectively improve the dividing diagnosis of cerebral palsy, and this method for different types of cerebral palsy in children has some guiding value. Key words: Nuclear magnetic resonance spectroscopy; Child cerebral palsy; Gross motor function measure