Abstract
Despite increases in screening and advances in treatment, breast cancer continues to be the most common cancer and cause of cancer deaths among women worldwide, and breast cancer rates have remained steady for decades. A new focus on population-level primary prevention is needed to tackle this disease at the most fundamental level. Unfortunately, only a small fraction of breast cancer research funds currently go to prevention. The California Breast Cancer Research Program (CBCRP) seeks to change this. In order to accelerate breast cancer primary prevention efforts, in 2018, CBCRP launched the Global Challenge to Prevent Breast Cancer, a prize competition to foster and disseminate new and innovative prevention research ideas. This Special Issue highlights the results of the Global Challenge and other CBCRP primary prevention efforts.
Highlights
Breast cancer is the most common cancer in women and the largest cause of cancer deaths among women worldwide: there were an estimated 2.1 million new cases and 626,679 deaths in 2018 [1]
Instead of looking at individual risk, if we look at risk across the population, we can identify and remove those common factors leading to a higher breast cancer incidence across the population [10]
Of the roughly USD 1 billion or more spent on breast cancer research each year across the globe, only a small fraction (5%–6%) is dedicated to prevention [14]
Summary
Breast cancer is the most common cancer in women and the largest cause of cancer deaths among women worldwide: there were an estimated 2.1 million new cases and 626,679 deaths in 2018 [1]. Despite accumulating evidence that indicates that most cancer cases could be prevented, few national prevention efforts have been launched.” [17] This Special Issue seeks to address this gap by highlighting cutting-edge ideas for future research on methods of prevention of breast cancer through social and environmental interventions. Each manuscript in this Special Issue examines an innovative method by which we could alter the trajectory of social and environmental exposures that impact the population incidence of breast cancer. A common theme across these articles is a focus on the primary prevention of breast cancer, especially at a population level
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