Abstract
Salmonella enterica subspecies enterica serovar Typhi is a rod-shaped, Gram-negative, facultatively anaerobic bacterium. It belongs to the family Enterobacteriaceae in the class Gammaproteobacteria, and has the capability of residing in the human gallbladder by forming a biofilm and hence causing the person to become a typhoid carrier. Here we present the complete genome of Salmonella enterica subspecies enterica serotype Typhi strain P-stx-12, which was isolated from a chronic carrier in Varanasi, India. The complete genome comprises a 4,768,352 bp chromosome with a total of 98 RNA genes, 4,691 protein-coding genes and a 181,431 bp plasmid. Genome analysis revealed that the organism is closely related to Salmonella enterica serovar Typhi strain Ty2 and Salmonella enterica serovar Typhi strain CT18, although their genome structure is slightly different.
Highlights
Salmonella enterica serovar Typhi is a particular Salmonella serovar that causes typhoid fever [13]
S. enterica serovar Typhi P-stx-12 was selected for sequencing because it was isolated from a typhoid carrier in India, where there is a high rate of typhoid fever cases
The genome of S. enterica serovar Typhi P-stx-12 was compared with the other two published S. enterica serovar Typhi genomes, CT18 and Ty2. Comparison between these three genomes revealed that the coding genes of S. enterica serovar Typhi P-stx-12 were 84% similar to those of CT18 [47] and Ty2 [9]
Summary
Salmonella enterica serovar Typhi is a particular Salmonella serovar that causes typhoid fever [13]. S. enterica serovar Typhi P-stx-12 was isolated from a typhoid carrier in Northern India, Uttar Pradesh, Varanasi in 2009. Cells of S. enterica serovar Typhi P-stx-12 were Gram-negative, motile, rod-shaped, and non-spore forming.
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
