Abstract
We present a genome assembly from an individual male Rattus norvegicus (the Norway rat; Chordata; Mammalia; Rodentia; Muridae). The genome sequence is 2.44 gigabases in span. The majority of the assembly is scaffolded into 20 chromosomal pseudomolecules, with both X and Y sex chromosomes assembled. This genome assembly, mRatBN7.2, represents the new reference genome for R. norvegicus and has been adopted by the Genome Reference Consortium.
Highlights
Rattus norvegicus is one of the most well-established experimental model organisms, with use of the species dating back to the mid-19th century (Modlinska & Pisula, 2020)
The longstanding use of R. norvegicus in the laboratory as a model organism has led to a multitude of discoveries, providing insight into human physiology, behaviour and disease
The complexity of R. norvegicus relative to many other model organisms, in addition to its well-characterised physiology, means that it is frequently used in cancer research, behavioral neuroscience, and the pharmaceutical industry
Summary
2. Kim Pruitt, National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, USA. Any reports and responses or comments on the article can be found at the end of the article. Species taxonomy Eukaryota; Metazoa; Chordata; Mammalia; Rodentia; Muridae; Rattus; Rattus norvegicus Berkenhout 1769 (NCBI:txid10116)
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