Abstract
ABSTRACT The detection of sonographic markers can modify the risk of fetal Down syndrome (DS) and is the basis of the so-called genetic sonogram. We present herein our experience with five cases found during early anomaly scan. They all share a common pathology- DS, but each has a different sonographic appearance with unique structural abnormalities. The detailed cases are desrcibed along with literature review of the sonographic findings. Using the ‘soft’ markers alone as a basis of deciding to offer amniocentesis will result in more fetal losses than DS detected. Therefore, the use of the genetic sonogram, especially in early pregnancy, based mainly on structural anomalies, will lessen the false-positive DS detection. How to cite this article Zalel Y. The Genetic Sonogram— Structural Anomalies in the Assessment of Trisomy 21: Case Reports and a Literature Review. Donald School J Ultrasound Obstet Gynecol 2013;7(4):475-480.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Donald School Journal of Ultrasound in Obstetrics and Gynecology
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
