Abstract
To investigate the hereditary model of lung cancer and to determine measurement of genetic factors on lung cancer. With methods of genetic epidemiology, 370 probands of lung cancer and 370 spouses of the probands ( control) were studied. The segregation ratio of lung cancer was 0. 15 and the genetic model of lung cancer belonged to polygenetics.The heritability of lung cancer was 24. 6%, 14. 6% for male and 37. 8% for female. The genetic model of lung cancer is polygenetics. The genetic susceptibility of female with lung cancer is higher than that of male. The genetic factor is one of the risk factors on lung cancer but the environmental factors are still the most important risk factors.
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