The function of the left atrium in hypertensive patients

Abstract

It has been established that the volume of OG is a marker of alteration of the diastolic function of the left ventricle. The aim of this study is to determine the relationship between left atrium remodeling and left ventricle diastolic dysfunction in hypertensive patients with preserved systolic function and the repercussions of high blood pressure (HTA) on size and function OG. A prospective study of 200 hypertensive patients in the cardiology department of the Avicenne military hospital in Marrakech during the period from July 2015 to July 2016. The average age of hypertensuve patients was 52 ± 5 years, 80 men, whose data were all evaluated by echocardiography measuring left atrium volumes during the reservoir, conduit and pump phases. Standard indices reflecting left ventricular filling were also assessed. Medium left atrium volume indexed for body surface was significantly higher in hypertensive patients–32.1 ± 4.6 mL/m 2 vs.21.72 (2.52) mL/m 2 . When compared to normal subjects, patients with mild diastolic dysfunction had lower corrected passive emptying volumes ( P < 0.001) and higher corrected active emptying volumes, thus leading to similar corrected total emptying volumes ( P < 0.001). However, patients with moderate diastolic dysfunction had smaller active emptying volumes, but higher passive and total emptying volumes when compared to normal controls and patients with mild diastolic dysfunction. The HTA induces an increase in the pump function and the reservoir function and an alteration of the function of the OG; these changes appear to be related to left ventricular hypertrophy and the degree of left ventricular diastolic dysfunction.