Abstract

The frontiers in brain imaging and neuromodulation: a New Challenge

Highlights

  • Modern scientific conceptualization of brain functions and localizations began to emerge from animal experiments, cadaver dissections, and clinical observations conducted by Broca (1865), Jackson (1873), and others in the mid 19th century

  • Ideas of regional brain functional localization and electrochemical neuronal transmission would later evolve into the contemporary neuronal network models that guide and inform much of the current applications of somatic treatments in neuropsychiatry

  • The relapse rates associated with it are very high. Both transcranial magnetic stimulation (TMS) and vagus nerve stimulation (VNS) are US FDA approved for depression and DBS is approved for obsessive compulsive disorder (OCD) under a humanitarian device exemption

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Summary

Introduction

Modern scientific conceptualization of brain functions and localizations began to emerge from animal experiments, cadaver dissections, and clinical observations conducted by Broca (1865), Jackson (1873), and others in the mid 19th century. Ideas of regional brain functional localization and electrochemical neuronal transmission would later evolve into the contemporary neuronal network models that guide and inform much of the current applications of somatic treatments in neuropsychiatry. The combination of transcranial magnetic stimulation (TMS) and other brain stimulation tools, offers unique opportunities to move away from the correlative nature of imaging results (Bohning et al, 1998).

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