Abstract
Background: The purpose of Saanen and Alpine raising farms is milk production, so control of mastitis is essential. Antibiotic resistance among mastitis pathogens has been increased by long-time usage of antibiotics. The aim of the present study was to isolate bacteria from mastitis cases in Saanen and Alpine goats and to determine their antibiotic resistance.
 Methods: Milk sample of 26 Saanen and 29 Alpine was cultured on microbiological media. Polymerase chain reaction was performed for the detection of Mycoplasma. Antibiotic resistance of the bacteria was tested by 12 antibacterial disks. Significant difference in resistance levels between Saanen and Alpine was assessed.
 Results: Mycoplasma spp. was detected in 12.73% of samples. The isolated bacteria were Escherichia coli (29.1%), Trueperella pyogenes (25.5%), Staphylococcus aureus (16.4%), Streptococcus agalactiae (9.1%), coagulase negative staphylococci (5.5%), and Corynebacterium pseudotuberculosis (1.8%). The significant difference was observed in antibiotic resistance to amoxicillin which was higher in Alpine.
 Conclusion: Accordingly using antibiotics more accurate and using antibiogram by clinician are necessary.
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