Abstract

The Fluorescent Probe Method in Investigation of the State of Erythrocyte Membranes in White Rats at Exposure to Chemical Environmental Factors

Highlights

  • The problem of diagnosing the consequences of harmful effects on the body of chemical environmental factors (CEF) is relevant, because today scientists of Ukraine and such countries as the United States of America, Great Britain, Germany and France are concerned about the growing pollution of drinking water and the world's oceans, and the entry of chemical pollutants into the human body with cosmetics, medicines, shampoos, detergents, materials for arranging apartments and many others [1,2,3,4,5,6]

  • The purpose of the presented work was to study the possibility of using the fluorescent probes method to diagnose the harmful effects of chemical factors on the example of polyethylene glycol on the organism of white rats by evaluating the state of erythrocyte membranes

  • In the case of erythrocytes of rats, which are toxic to polyethylene glycol (PEG)-400, there is a marked decrease in the fluorescence intensity of all the probes used

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Summary

Introduction

The problem of diagnosing the consequences of harmful effects on the body of chemical environmental factors (CEF) is relevant, because today scientists of Ukraine and such countries as the United States of America, Great Britain, Germany and France are concerned about the growing pollution of drinking water and the world's oceans, and the entry of chemical pollutants into the human body with cosmetics, medicines, shampoos, detergents, materials for arranging apartments and many others [1,2,3,4,5,6]. PEG is used to soften some plastics (polyethylene, polyvinyl chloride, cellulose ether membranes in filters, etc.) that are used to store and transport food. According to the latest research of foreign scientists, plastic components can migrate from products made from them to foodstuffs during storage, processing and transportation, and potentially affect human health [1, 6].

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