Abstract
The changes in the Na/K ratio were followed on 24-hour samples of urine repeatedly taken at 7-day intervals during multiple X-irradiation of mice with single exposures of 200 r (up to a total exposure of 1200 r). The fluctuation of the Na/K ratio in the course of the experiments on the individual animals was analysed by using certain principles of time series statistics. Three characteristics were chosen, i.e. regularity of fluctuation, mean amplitude and level of fluctuation of the Na/K ratio. It was shown that low and high amplitudes of fluctuation, accompanied by fluctuation about low and high levels and the least regular type of fluctuation, constitute, from the viewpoint of radiosensitivity of the experimental animals, an unfavourable prognostic sign. The authors stress the importance of these findings for solving problems relating to differing individual sensitivity to radiation.
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