The first year of Sars-Cov-2: Which mutations spread rapidly around the word? Minireview

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a worldwide crisis with profound effects on both public health and the economy. In order to combat the Sars-Cov-2 pandemic, research groups have shared viral genome sequence data through the Global Initiative on Sharing All Influenza Data (GISAID). SARS-CoV-2 is an RNA virus, which is a family with significant adaptive evolution). Worldwide research groups are generating and sharing SARS-CoV-2 proteome sequence data in a rapid fashion as a global effort to combat the COVID-19 pandemic. The rapid spread of an alternative variant of coronavirus has been blamed for the introduction of strict tier four mixing rules for many people, strict restrictions on mixing at Christmas in England, Scotland and Wales, and other countries placing the United Kingdom on a travel ban. So how has it gone from being non-existent to the foremost common sort of the virus in parts of England during a matter of months? Now that vaccines have been developed and are being deployed to address the COVID-19 pandemic, a major concern is the emergence of mutations in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that confer immune escape or enhanced fitness. As such, it is important to assess how rapidly SARS-CoV-2 proteins are mutating . While it is currently unclear if these mutations benefit the virus, their continued surveillance and the detection of new proteome variants are likely to illuminate key aspects of viral function. The government’s advisers on new infections now say they need “high” confidence that it’s more ready to transmit than other variants.